This Set decreases the target’s MAX HP by 30% of the damage dealt by the wearer.

This is a good Set to counter tanky Champions with good self-sustain that usually heal themselves up to high HP before you’re able to take them down. This is because when fighting against a Destroy Set, each of their heals will be worth less. When attacking with a Destroy Set, the target’s MAX HP cannot be decreased by more than 8% with each attack. The effect applies per Skill, not per hit, so multi-hit Skills accumulate and the HP destroyed is increased up to the 8% limit. Over the course of the battle, the target’s MAX HP cannot drop below 40% of the original value.
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